Practitioner grade
Cortisol rhythm and sex hormones (at-home saliva)
NutriPath

Cortisol rhythm and sex hormones (at-home saliva)

NutriPath pathology testing

An at-home saliva profile combining cortisol measurements across the day with sex hormone measurements. Collection timing is part of the test, so plan the samples using the kit instructions.

About this test

A single blood cortisol measurement tells you almost nothing, because cortisol is supposed to rise and fall across the day. What matters is the rhythm. This saliva panel captures four cortisol readings at the biologically meaningful points (shortly after waking, noon, evening and bedtime) alongside your free bioavailable sex hormones (oestradiol, progesterone, testosterone) and DHEA. The rhythm tells you whether your HPA axis is responding appropriately to daylight and stress or whether it has flattened, reversed or become erratic. The sex hormone layer shows you how your reproductive hormones sit in the context of your stress response, a distinction that is often missed in single point testing. Completed at home over one day and mailed in a prepaid envelope.

What it measures 6 markers
  • Cortisol (x4 points)
  • DHEA
  • Oestradiol (E2)
  • Progesterone
  • Testosterone (Free)
  • Progesterone:Oestradiol Ratio
Test details
CollectionAt-home collection kit
LabNutriPath
When to expect your results

3 to 5 days after the laboratory receives your sample

Allow additional time for order and referral checks, kit delivery, completing your collection and return postage. The laboratory estimate starts once your sample reaches the testing laboratory.

See the steps from order to results
$342.00
Practitioner consult session A 15-minute consultation. An email link will be included in your order confirmation to make the booking.
Optional 1:1 with our clinical team · $49
What it measures 6 markers
Cortisol (x4 points)
Saliva

The four point rhythm is far more informative than any single cortisol reading. Reveals flattening (burnout pattern), reversed rhythm (high at night, low in morning) or elevation at specific times.

DHEA
Saliva

The adrenal hormone that counter balances cortisol. Low DHEA with elevated cortisol is the classic chronic stress pattern.

Oestradiol (E2)
Saliva

Saliva reflects free, unbound oestradiol, which is the biologically active fraction.

Progesterone
Saliva

The free fraction of progesterone, which correlates with symptoms more reliably than total serum levels.

Testosterone (Free)
Saliva

Women produce testosterone too. Low free testosterone is associated with low libido, low mood and reduced muscle mass.

Progesterone:Oestradiol Ratio
Calculated

One of the most useful ratios in assessing perimenopausal symptom drivers. Low progesterone relative to oestradiol often explains PMS, sleep and mood symptoms in the late 30s and 40s.

Your testing journey

From your order to your results.

Order and referral review, sample collection, laboratory analysis and discussing your report are separate stages. Your test’s processing estimate covers the laboratory stage.

ORDER

Order and referral check

Order your test. We review the order and check whether a referral or other information is required before the next step can begin.

ARRANGE

Your kit is posted

Once the required checks are complete, your collection kit is posted to you. Delivery time is additional to laboratory processing. Read all instructions before you start.

COMPLETE

Collect and return

Complete the sample collection at home and return it using the supplied instructions. Allow time for preparation, any timed collections and return postage.

RESULTS

Laboratory processing

Once the laboratory receives your sample, it completes the analysis and prepares your report. Discuss the findings with your practitioner alongside your symptoms and health history.

Preparing for this test

Read the instructions supplied for your exact test before collecting. Check food, drink, medicines, timing, storage and return requirements with your practitioner. Do not stop prescribed medicines without advice.

Does the estimate include postage?

No. The laboratory estimate does not include order review, referral checks, delivery to you, the time you take to collect, or transport back to the testing laboratory. These stages make up the full order-to-results journey.

Need results by a particular date?

Check with Evergreen before ordering so the referral requirements, collection timing, delivery and laboratory estimate can be considered together.

Ask Evergreen about timing

Before you order.

Practical questions about choosing, preparing for and reviewing this test.

Do I need a consultation or referral?

Requirements vary by test. Check the ordering options on this page and confirm any referral requirements with Evergreen. A laboratory’s practitioner-referral requirement is separate from whether you need to book an additional consultation.

Should I change medicines or supplements before testing?

Do not stop prescribed medicines on your own. Tell your practitioner what you take and follow the preparation instructions for this test. Timing, fasting and other requirements depend on the sample and markers being measured.

Does the test tell me what treatment I need?

A result is one part of an assessment. A qualified practitioner should interpret it alongside your symptoms, history and medicines. Check whether a results consultation is included in your purchase or needs to be booked separately.

How should I read the reference ranges?

Use the reference intervals and units on your own laboratory report. Ranges can vary with the method and patient factors. A result inside or outside a range does not establish a diagnosis on its own.

Who is the testing provider?

These tests are supplied through NutriPath, a medical laboratory founded in 2011 and based in Burwood, Victoria. NutriPath works through a practitioner-referral system.

About NutriPath and its laboratory credentials

When does the turnaround estimate start?

The laboratory estimate is not the time from placing your order. Allow time for referral checks, kit dispatch where needed, sample collection and transport before processing. The estimate varies by test, and specialist or overseas analysis can take longer.

Follow the estimate for your specific test. A quoted 3–5 business days does not include the whole ordering and collection journey.

Where do I find preparation and collection instructions?

Use the instructions supplied for your exact kit. Blood tests may require an arranged collection appointment; receiving a kit does not mean you should draw blood yourself. Saliva, urine, stool and breath tests each have different preparation requirements.

NutriPath preparation and collection guidance

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