"This was the first time someone showed me what was happening and what to do about it. "
Practitioner grade
Practitioner only
Specialised pro-resolving mediators (SPMs)
Concentrated pro resolving mediators for stubborn inflammation
SPM Active provides concentrated Specialised Pro-Resolving Mediators (SPMs), standardised lipid mediators that actively resolve inflammation and restore immune homeostasis.
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Practitioner consult session
A 15-minute consultation. An email link will be included in your order confirmation to make the booking.
Optional 1:1 with our clinical team · $49
TGA-listed AUST L
Practitioner-grade formula
Clinician-reviewed before dispatch
Ships in 2 business days
What's in it
Each ingredient is in its most bioavailable form, at a clinically meaningful dose. No fillers, no token amounts, no marketing-led blends.
Standardised EPA/DHA-derived lipid mediator concentrate
Specialised Pro-Resolving Mediators (SPM Active concentrate)
Metagenics-proprietary concentrated SPM fraction. Contains resolvins, protectins and maresins — the active inflammation resolution signals produced from omega-3 fatty acid metabolism.
Included
Always read the label and follow directions for use. Vitamins and minerals can only be of assistance if dietary intake is inadequate. If symptoms persist, consult a healthcare professional.
How to take it
Simple to take, with a few timing notes that make a real difference to absorption.
As directed by your practitioner. Typically 1 capsule twice daily with food.
Contains fish (fish oil derived). May interact with anticoagulant medications. Dietary supplements should not replace a balanced diet.
Real people. Real impact.
Patients following practitioner-designed protocols, sharing their outcomes in their own words.
"My ferritin had been low-normal for three years. The protocol made a real difference within six weeks."
"Someone finally put all the pieces together. Clear, specific and actually useful."
Trustpilot · 4.8/5 from 892 reviewsGoogle · 4.9/5 from 412 reviewsPractitioner referral · 97% would recommend
Part of the Energy & Fatigue hub. Explore all protocols, supplements and investigations.
Back to Energy & Fatigue →Frequently asked.
Common questions about how OptiLabs works: testing, supplements, clinician review, returns and timing.
How long before I notice benefit?
SPM mechanisms work through active resolution signalling. Clinical response varies by condition severity and chronicity. Most practitioners assess response at 8–12 weeks.
Are the supplements safe?
All carry an AUST L designation from the TGA. Every order is reviewed by a clinician before dispatch.
Do I need a referral?
No. All tests are available to order directly. Our lab partner is NATA and RCPA accredited, operating as a direct-access pathology service.
Begin your investigation
Personalised health. Clinical rigour. Delivered to you.
A proper investigation into what's driving your symptoms, with a protocol built around your results, not a generic recommendation.