Practitioner grade
RN Labs BioActive B-Complex, 60 capsules on a beige stone platform
Active-form B complex
RN Labs

Active-form B complex

A comprehensive B-vitamin complex providing all eight B vitamins in their most bioactive, methylated or coenzyme forms. Folinic acid and hydroxy-B12 are included specifically to support those with MTHFR gene variants.

$39.95 $41.05
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Product details

See what’s in it, how to take it and the important information to know before you order.

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RN Labs' BioActive B-Complex 60 capsules High-Potency Active B-Vitamin Complex Well-balanced, broad-spectrum B vitamin support Pure and potent low-excipient formula Provides highly bioactive forms without causing excess over-stimulation Folinic acid readily converts to methylfolate without delivering excess external methyl groups Hydroxy-B12 converts to methyl-B12 in the body, without introducing external methyl groups Provides a highly versatile foundation to further supplementation (including methyl forms) Provides a non-flushing form of vitamin B3 Provides a form of vitamin B6 not associated with peripheral neuropathy Per bottle: 60 vegetarian capsules (1 capsule = 1 serving) Suggested use Adults: Take 1 capsule daily or as prescribed by your healthcare practitioner. Product Education: RN Labs BioActive B-Complex is a pure, balanced and hypoallergenic source of metabolically active forms of B complex vitamins, providing a highly versatile foundation to further supplementation (including the methylated vitamin forms). The vitamins in BioActive B-Complex have been demonstrated to support a range of metabolic processes, including energy production, detoxification processes, neurological health, stress response and hormone balance. The bioactive, yet unmethylated, forms are used to support optimal activity, without causing over-stimulation, particularly in sensitive patients. Hydroxocobalamin Vs. CyanocobalaminHydroxocobalamin and cyanocobalamin were compared for their efficacy in lowering elevated blood methylmalonic acid and urine homocysteine in cobalamin-deficient patients. Each patient did experience a significant decrease in urine methylmalonic acid excretion while receiving cyanocobalamin, but levels remained at least 10 times normal. Cyanocobalamin treatment resulted in a decrease of plasma homocysteine to near normal in one patient but had no effect on plasma homocysteine in another patient. Each patient was then switched to hydroxocobalamin where they experienced a decrease in methylmalonic acid levels to the limits of detection. Plasma homocysteine values while taking hydroxocobalamin also remained significantly decreased at < 5 nmol/ml in all patients. In one patient, who continued to receive cyanocobalamin therapy for more than 1 year, growth rates (height, weight, and head circumference) were very poor. After initiation of hydroxocobalamin, growth parameters normalised with growth rates returning above normal. Authors concluded that cyanocobalamin treatment is inadequate in the treatment of patients with cobalamin C disease, and appropriate management should include only the hydroxocobalamin form of cobalamin. Pure & Free From:This product does NOT contain wheat, gluten, dairy, lactose, egg, corn, yeast, soy, artificial colours, artificial sweeteners, or artificial flavours. This product also does not contain synthetic preservatives, stearate lubricants and other
What's in it 8 active ingredients

Thiamine (B1)

Thiamine HCl

Included

Cofactor for pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase — essential for carbohydrate energy metabolism.

Riboflavin (B2)

Riboflavin 5-phosphate (active)

Included

Coenzyme form (FMN) required for the electron transport chain and fatty acid beta-oxidation.

Niacin (B3)

Inositol hexanicotinate (non-flushing)

Included

Non-flushing form of niacin supporting NAD+ synthesis without the vasodilatory effects of nicotinic acid.

Pantothenic Acid (B5)

Calcium pantothenate

Included

Required for coenzyme A synthesis — essential for fatty acid metabolism and the citric acid cycle.

Pyridoxine (B6)

Pyridoxal-5-phosphate (P5P)

Included

Active coenzyme form of B6, bypassing the liver conversion step. Required for amino acid metabolism, neurotransmitter synthesis and haemoglobin production.

Folate (B9)

Folinic acid (5-formyl-THF)

Included

Folinic acid converts to methylfolate in the body without requiring the MTHFR enzyme — providing reliable folate support regardless of MTHFR genotype, without introducing excess methyl groups.

Vitamin B12

Hydroxocobalamin

Included

Converts to both methyl-B12 and adenosyl-B12 in the body. Provides complete B12 support without introducing external methyl groups — ideal where methylation load management is important.

Biotin (B7)

D-Biotin

Included

Essential cofactor for carboxylase enzymes involved in fatty acid synthesis, gluconeogenesis and amino acid metabolism.
How to take it
1-2 capsules daily with food, or as directed by your practitioner.
Warnings and important information
Dietary supplements should not replace a balanced diet. Consult your practitioner if you are taking medications that interact with folate or B12 (including methotrexate). Not recommended during pregnancy without practitioner guidance on folate dose.
Always read the label and follow directions for use. Vitamins and minerals can only be of assistance if dietary intake is inadequate. If symptoms persist, consult a healthcare professional.

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