Designs for Health Liposomal Glutathione (COLD)
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Designs for Health's Liposomal Glutathione 50ml
Reduce free radicals formed in the body and maintain health immune system function
- Liposomal technology for superior absorption and delivery
- Orange peppermint flavour for easy compliance
- Supports liver health
- Reduces free radicals formed in the body
- Maintains healthy immune system function
Servings per bottle: 16 (0.5ml = 1 pump)
Directions for use
Adults: Take 3 ml (6 pumps) in mouth once daily or as directed by your healthcare professional. Hold in mouth for 30 seconds before swallowing.
Allergen Information
Does not contain: gluten, dairy, lactose or nuts.
Storage Instructions
Store at 2–8°C. Refrigerate do not freeze.
Product Education:
Glutathione is an endogenous antioxidant comprising of glutamate, cysteine and glycine that continually converts between 4 different forms depending on the body’s physiological requirements. Present in relatively high concentrations in many tissues, optimal levels of glutathione are essential for many functions in the body including reducing oxidative stress, maintaining redox balance, enhancing metabolic detoxification processes, as well as enhancing hepatic conversion and immune system functionality. Many factors influence the body’s need for glutathione including weight gain, stress, aging, increased exposure to medications, environmental toxin exposure (e.g. heavy metals, solvents, pesticides, alcohol), smoking, poor nutrition and ultraviolet radiation. While glutathione is naturally present in some foods, the level of intake that can be attained via the diet alone is minimal due to significant hydrolysis in the gastrointestinal tract, low bioavailability and the complexity of maintaining glutathione levels in the body.
Liposomal Technology
Supporting optimal glutathione levels in the body requires overcoming issues associated with oral glutathione intake, including extensive gastrointestinal hydrolysis and suboptimal bioavailability. Combining the biologically active reduced form of oral glutathione (GSH) with liposomal technology provides an effective delivery system specifically designed to overcome these issues by acting as efficient transport carrier for peptides and proteins. Liposomes can enhance the gastrointestinal stability, bioavailability and absorption of glutathione due to their bilayer structure, with a lipophilic phospholipid layer surrounding a hydrophilic core encapsulating glutathione. The structural similarity of liposomes to endogenous cell membranes is a key factor in their capacity to improve glutathione bioavailability and absorption, thereby supporting the full spectrum of glutathione’s therapeutic benefits in the body.
Antioxidant
The significance of glutathione’s potent antioxidant activity is highlighted by its synthesis in every cell cytoplasm in the body. It is considered to be the most important endogenous hydrophilic, intracellular antioxidant due to its ability to neutralize lipid peroxides, hydrogen peroxides and reactive oxygen species, regenerate other antioxidants (vitamins C and E) as well as conjugate and inhibit the oxidative effects of exogenous toxins. The importance of optimal levels of the active form of glutathione in the body is also observed in the fluctuating ratio between its reduced (GSH) and oxidized (GSSH) forms, with high GSSH levels correlated with elevated oxidative stress levels, the effects of which being counteracted by higher GSH concentrations in the body.
Immune
Glutathione is also important for healthy immune system function via several mechanisms. These include protection of immune cell integrity and activity via both antioxidant processes and by inhibiting the cell damaging effects of complement system proteins. Glutathione also promotes the synthesis, proliferation and activity of natural killer cells, T-cells, lymphocytes and dendritic cells. The importance of glutathione for immune system health is also observed by low levels of glutathione in the body associated with suboptimal immune strength and function.
Liver
Almost 25% of the body’s total glutathione is concentrated in the liver, emphasising the importance of optimal glutathione levels for healthy liver function. Glutathione supports liver function by acting as a key substrate of the hepatic phase 2 glutathione-S-transferase enzymatic pathway that conjugates exogenous toxins and xenobiotics (e.g. medications, pesticides, alcohol), and as part of glutathione peroxidase that neutralises hydrogen peroxide free radicals and lipid oxidative damage.
Warnings
- Contraindicated for use during pregnancy and lactation.
- Contains 12% ethanol.
- Adults only.
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