{"product_id":"nutripath-precision-analytical-comprehensive-hormone-test-at-home-dried-urine","title":"Comprehensive hormone test (at-home dried urine)","description":"\u003ch2 class=\"product-marketing-headline\"\u003eThe gold standard hormone test, done at home over a single day\u003c\/h2\u003e\u003cp class=\"product-tagline\"\u003e\u003cem\u003eThe most comprehensive view of hormone metabolism available. Sex hormones, cortisol rhythm, melatonin and detoxification pathways in a single dried urine test.\u003c\/em\u003e\u003c\/p\u003e\u003cp class=\"product-brand-attribution\"\u003eTest processed by \u003cstrong\u003eNutriPath (Precision Analytical)\u003c\/strong\u003e\u003c\/p\u003e\u003cdiv class=\"product-short-description\"\u003e\u003cp\u003eThe gold standard hormone test used by functional medicine practitioners worldwide. Measures oestrogen and its metabolites (showing whether you clear oestrogen down protective or risky pathways), progesterone, testosterone, the four point cortisol rhythm, DHEA, melatonin and organic acid markers. Performed at home with dried urine samples.\u003c\/p\u003e\u003c\/div\u003e\u003cdiv class=\"product-long-description\"\u003e\u003cp\u003eEndoMAP (the DUTCH Complete panel from Precision Analytical) is not a standard hormone test. Where a serum panel gives you a snapshot of circulating hormones, DUTCH captures the metabolites, showing not just how much oestrogen you have but which pathway your body is using to clear it. This matters because oestrogen metabolism splits into a protective pathway (2-OH) and a more concerning pathway (4-OH, 16-OH). The ratio between these is one of the most useful data points for anyone with a family history of hormone sensitive cancers or who is considering HRT. Beyond oestrogen, the panel covers the four point cortisol rhythm, free and metabolised cortisol, DHEA, progesterone metabolites, testosterone and its androgenic conversions, melatonin, and functional markers of B6 and glutathione status. Completed at home over a single day with four dried urine strips.\u003c\/p\u003e\u003c\/div\u003e\u003cdiv class=\"product-ingredients\"\u003e\n\u003ch3\u003eWhat it measures\u003c\/h3\u003e\n\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eBiomarker\u003c\/th\u003e\n\u003cth\u003eSample\u003c\/th\u003e\n\u003cth\u003eReference Range\u003c\/th\u003e\n\u003cth\u003eWhat it tells you\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eOestrogens and Metabolites\u003c\/td\u003e\n\u003ctd\u003eDried Urine\u003c\/td\u003e\n\u003ctd\u003eRatio dependent\u003c\/td\u003e\n\u003ctd\u003eMeasures oestrone, oestradiol, oestriol and the 2-OH, 4-OH and 16-OH metabolite pathways. Reveals whether oestrogen is clearing down protective or risky pathways.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eProgesterone and Metabolites\u003c\/td\u003e\n\u003ctd\u003eDried Urine\u003c\/td\u003e\n\u003ctd\u003eCycle dependent\u003c\/td\u003e\n\u003ctd\u003eFree progesterone plus alpha and beta pregnanediol metabolites. More informative than serum progesterone for understanding functional progesterone activity.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eTestosterone and Androgens\u003c\/td\u003e\n\u003ctd\u003eDried Urine\u003c\/td\u003e\n\u003ctd\u003eAge and sex dependent\u003c\/td\u003e\n\u003ctd\u003eTotal testosterone plus the DHT and etiocholanolone conversion pathways. Important for acne, androgenic symptoms and PCOS assessment.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eFour Point Cortisol Rhythm\u003c\/td\u003e\n\u003ctd\u003eDried Urine\u003c\/td\u003e\n\u003ctd\u003eNormal diurnal curve expected\u003c\/td\u003e\n\u003ctd\u003eCaptures waking, morning, afternoon and evening cortisol. Shows HPA axis rhythm and burnout patterns.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eDHEA-S\u003c\/td\u003e\n\u003ctd\u003eDried Urine\u003c\/td\u003e\n\u003ctd\u003eAge dependent\u003c\/td\u003e\n\u003ctd\u003eThe precursor hormone that declines with age and stress.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eMelatonin (6-OH Melatonin Sulphate)\u003c\/td\u003e\n\u003ctd\u003eDried Urine\u003c\/td\u003e\n\u003ctd\u003eOvernight measurement\u003c\/td\u003e\n\u003ctd\u003eReflects overnight melatonin production, relevant to sleep, immune function and hormone balance.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eOrganic Acid Markers\u003c\/td\u003e\n\u003ctd\u003eDried Urine\u003c\/td\u003e\n\u003ctd\u003eFunctional ranges\u003c\/td\u003e\n\u003ctd\u003eIncludes 8-OHdG (oxidative stress), vanilmandelate and homovanillate (dopamine and noradrenaline metabolism), B6 and glutathione status markers.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\u003cdiv class=\"product-how-to-take\"\u003e\n\u003ch3\u003eHow to collect and what to expect\u003c\/h3\u003e\n\u003cp\u003eCompleted at home over a single day. Collect four urine samples on dried filter strips at: bedtime, overnight wake (optional, for CAR measurement), waking, and two hours after waking. Dry the strips overnight, place in the supplied envelope, and mail back. Timing within cycle matters for women with periods: days 19 to 22 (mid luteal) are preferred. Results in 14 to 21 business days with a detailed clinical report.\u003c\/p\u003e\n\u003c\/div\u003e\u003cdiv class=\"product-warnings\"\u003e\n\u003ch3\u003eWarnings and cautions\u003c\/h3\u003e\n\u003cp\u003eThis is a health information test. Do not make medication decisions based on these results alone. HRT, oral contraceptives and corticosteroid medication will affect readings. Discuss timing of testing with your prescriber if you take these medications. Interpretation is complex and typically requires a functional medicine or integrative practitioner.\u003c\/p\u003e\n\u003c\/div\u003e\u003cdiv class=\"product-faqs\"\u003e\n\u003ch3\u003eCommon questions\u003c\/h3\u003e\n\u003cdetails\u003e\u003csummary\u003e\u003cstrong\u003eWhy is this considered the gold standard?\u003c\/strong\u003e\u003c\/summary\u003e\u003cp\u003eThe DUTCH methodology measures hormone metabolites, not just hormone levels. This gives a functional view of how your body is processing hormones, not just what is circulating. The 2-OH, 4-OH and 16-OH oestrogen pathway data is not available on any serum test.\u003c\/p\u003e\u003c\/details\u003e\u003cdetails\u003e\u003csummary\u003e\u003cstrong\u003eHow does this compare to saliva testing?\u003c\/strong\u003e\u003c\/summary\u003e\u003cp\u003eSaliva captures the free hormone fraction at a single point. DUTCH captures metabolites, cortisol rhythm, and substantially more data points. DUTCH is more comprehensive but also more expensive. For simple rhythm assessment, saliva is adequate. For complex hormonal cases or cancer risk assessment, DUTCH is the better choice.\u003c\/p\u003e\u003c\/details\u003e\u003cdetails\u003e\u003csummary\u003e\u003cstrong\u003eWhen in my cycle should I test?\u003c\/strong\u003e\u003c\/summary\u003e\u003cp\u003eDays 19 to 22 (mid luteal phase) are optimal for a complete picture. If cycles are absent (menopause, amenorrhoea), any day is acceptable. The order comes with specific guidance for your situation.\u003c\/p\u003e\u003c\/details\u003e\u003cdetails\u003e\u003csummary\u003e\u003cstrong\u003eCan I test while on HRT?\u003c\/strong\u003e\u003c\/summary\u003e\u003cp\u003eYes, and the test is often used specifically to monitor HRT metabolism. However the interpretation differs from a baseline test. Your practitioner needs to know your HRT regimen and timing to interpret correctly.\u003c\/p\u003e\u003c\/details\u003e\n\u003c\/div\u003e\u003cdiv class=\"product-clinical-evidence\"\u003e\n\u003ch3\u003eClinical evidence\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/28938555\/\" target=\"_blank\" rel=\"noopener\"\u003eDried urine measurement of oestrogen metabolites\u003c\/a\u003e: Validation of dried urine methodology for oestrogen metabolite measurement.\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/10734996\/\" target=\"_blank\" rel=\"noopener\"\u003e2-OH to 16-OH oestrogen ratio and breast cancer risk\u003c\/a\u003e: Landmark paper establishing the clinical significance of oestrogen metabolite pathways.\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/24635534\/\" target=\"_blank\" rel=\"noopener\"\u003eCortisol metabolism in dried urine\u003c\/a\u003e: Validates dried urine methodology for comprehensive cortisol assessment.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e","brand":"NutriPath (Precision Analytical)","offers":[{"title":"Default Title","offer_id":52591882731794,"sku":"OPTI-NUTRIPATH-PRECISION-ANALYTICAL-COMPREHEN","price":387.0,"currency_code":"AUD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0557\/2087\/0083\/files\/nutripath-precision-analytical-comprehensive-hormone-test-at-home-dried-urine.jpg?v=1786431181","url":"https:\/\/optilabs.com.au\/products\/nutripath-precision-analytical-comprehensive-hormone-test-at-home-dried-urine","provider":"OptiLabs by Evergreen Doctors","version":"1.0","type":"link"}