{"product_id":"nutripath-complete-four-part-gut-investigation","title":"Complete four-part gut investigation","description":"\u003ch2 class=\"product-marketing-headline\"\u003eEverything about your gut in one coordinated investigation\u003c\/h2\u003e\u003cp class=\"product-tagline\"\u003e\u003cem\u003eThe most comprehensive single gut test available. Microbiome, digestion, inflammation and permeability in one investigation.\u003c\/em\u003e\u003c\/p\u003e\u003cp class=\"product-brand-attribution\"\u003eTest processed by \u003cstrong\u003eNutriPath\u003c\/strong\u003e\u003c\/p\u003e\u003cdiv class=\"product-short-description\"\u003e\u003cp\u003eCombines complete microbiome mapping, digestive function markers, inflammatory markers and intestinal permeability assessment in one coordinated test. For complex cases where multiple aspects of gut function need investigation simultaneously.\u003c\/p\u003e\u003c\/div\u003e\u003cdiv class=\"product-long-description\"\u003e\u003cp\u003eWhen gut symptoms are complex, chronic, or have not responded to standard interventions, testing one aspect of gut function at a time can mean missing the full picture. The 4-Pillar Gut Profile assesses all four domains simultaneously: microbiome composition and diversity, digestive and absorptive function, inflammation and immunity, and intestinal barrier integrity. The result is a coordinated view that reveals patterns like dysbiosis driving permeability driving autoimmune activity, or low digestive enzyme output driving bacterial overgrowth driving inflammation. This is the test to consider when a standard microbiome test has not explained the full symptom picture, when multiple gut interventions have produced partial but incomplete results, or when an initial comprehensive baseline is worth the investment to avoid sequential testing costs.\u003c\/p\u003e\u003c\/div\u003e\u003cdiv class=\"product-ingredients\"\u003e\n\u003ch3\u003eWhat it measures\u003c\/h3\u003e\n\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eBiomarker\u003c\/th\u003e\n\u003cth\u003eSample\u003c\/th\u003e\n\u003cth\u003eReference Range\u003c\/th\u003e\n\u003cth\u003eWhat it tells you\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003ePillar 1: Microbiome Composition\u003c\/td\u003e\n\u003ctd\u003eStool (PCR)\u003c\/td\u003e\n\u003ctd\u003eComprehensive bacterial profile\u003c\/td\u003e\n\u003ctd\u003eBeneficial bacteria, opportunistic organisms, parasites, yeast and Helicobacter pylori. The structural map of your gut ecosystem.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePillar 2: Digestive Function\u003c\/td\u003e\n\u003ctd\u003eStool\u003c\/td\u003e\n\u003ctd\u003ePancreatic elastase, faecal fats, secretory IgA\u003c\/td\u003e\n\u003ctd\u003eMeasures how well you are producing digestive enzymes, absorbing fats, and mounting mucosal immune responses.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePillar 3: Inflammation and Immunity\u003c\/td\u003e\n\u003ctd\u003eStool\u003c\/td\u003e\n\u003ctd\u003eCalprotectin, lactoferrin, beta glucuronidase\u003c\/td\u003e\n\u003ctd\u003eMarkers of active gut inflammation, immune activation and enzyme activity. Distinguishes IBD patterns from functional disorders.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003ePillar 4: Intestinal Barrier Function\u003c\/td\u003e\n\u003ctd\u003eUrine (6 hour collection) + stool\u003c\/td\u003e\n\u003ctd\u003eLactulose mannitol ratio, zonulin\u003c\/td\u003e\n\u003ctd\u003eFunctional barrier integrity assessment. Tells you whether leaky gut is contributing to the picture.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\u003cdiv class=\"product-how-to-take\"\u003e\n\u003ch3\u003eHow to collect and what to expect\u003c\/h3\u003e\n\u003cp\u003eCompleted at home across two collection processes. Stool collection for microbiome and digestive markers. Separate urine collection for intestinal permeability after drinking the sugar solution. Comprehensive kit includes all components and instructions. Results and detailed interpretive report in 21 to 28 business days.\u003c\/p\u003e\n\u003c\/div\u003e\u003cdiv class=\"product-warnings\"\u003e\n\u003ch3\u003eWarnings and cautions\u003c\/h3\u003e\n\u003cp\u003eThis is a health information test. Not appropriate within 4 weeks of antibiotic use or 2 weeks of probiotic supplement use. Complex interpretation benefits from a practitioner familiar with functional gut medicine.\u003c\/p\u003e\n\u003c\/div\u003e\u003cdiv class=\"product-faqs\"\u003e\n\u003ch3\u003eCommon questions\u003c\/h3\u003e\n\u003cdetails\u003e\u003csummary\u003e\u003cstrong\u003eIs this overkill for basic gut symptoms?\u003c\/strong\u003e\u003c\/summary\u003e\u003cp\u003eFor simple, recent onset or predictable pattern symptoms, yes. A more focused test (microbiome, or breath test, or calprotectin) is usually adequate. This panel is specifically for complex, chronic cases where previous testing has not explained the picture, or where the investment in a complete baseline will save money on sequential testing.\u003c\/p\u003e\u003c\/details\u003e\u003cdetails\u003e\u003csummary\u003e\u003cstrong\u003eHow does this compare to GI-MAP or other comprehensive stool tests?\u003c\/strong\u003e\u003c\/summary\u003e\u003cp\u003eGI-MAP is a similar comprehensive stool analysis. The 4-Pillar adds permeability assessment (urine based) and is a more coordinated multi domain investigation. Cost and turnaround differ between providers.\u003c\/p\u003e\u003c\/details\u003e\u003cdetails\u003e\u003csummary\u003e\u003cstrong\u003eWhat is the typical workflow after results?\u003c\/strong\u003e\u003c\/summary\u003e\u003cp\u003ePractitioners typically use the results to prioritise a treatment sequence: treat infections or overgrowth first, support digestion, address inflammation, restore barrier, rebuild microbiome. The coordinated data makes the sequencing clearer than piecemeal testing.\u003c\/p\u003e\u003c\/details\u003e\u003cdetails\u003e\u003csummary\u003e\u003cstrong\u003eHow often should this be repeated?\u003c\/strong\u003e\u003c\/summary\u003e\u003cp\u003eThis is typically a one time comprehensive baseline or a before and after measurement for a long treatment protocol (6 months minimum between tests). Ongoing monitoring uses simpler focused tests.\u003c\/p\u003e\u003c\/details\u003e\n\u003c\/div\u003e\u003cdiv class=\"product-clinical-evidence\"\u003e\n\u003ch3\u003eClinical evidence\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/31578516\/\" target=\"_blank\" rel=\"noopener\"\u003eComprehensive gut function assessment\u003c\/a\u003e: Rationale for multi domain gut assessment in complex cases.\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/22109896\/\" target=\"_blank\" rel=\"noopener\"\u003eGut barrier, microbiome and inflammation interactions\u003c\/a\u003e: Why the four domains are clinically interconnected.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e","brand":"NutriPath","offers":[{"title":"Default Title","offer_id":52591877783826,"sku":"OPTI-NUTRIPATH-COMPLETE-FOUR-PART-GUT-INVESTI","price":1097.0,"currency_code":"AUD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0557\/2087\/0083\/files\/nutripath-complete-four-part-gut-investigation.jpg?v=1786431161","url":"https:\/\/optilabs.com.au\/products\/nutripath-complete-four-part-gut-investigation","provider":"OptiLabs by Evergreen Doctors","version":"1.0","type":"link"}