{"product_id":"mutaflor-3-pack-bundle","title":"E. coli Nissle 1917 probiotic 3-pack bundle","description":"\u003cp\u003eThis three-pack contains three units of the original single product. Stock is shared with the original product.\u003c\/p\u003e\u003ch2 class=\"product-marketing-headline\"\u003eA 120 year old probiotic with unmatched clinical evidence\u003c\/h2\u003e\u003cp class=\"product-tagline\"\u003e\u003cem\u003eThe original E. coli Nissle 1917 probiotic, 120 years of clinical evidence.\u003c\/em\u003e\u003c\/p\u003e\u003cdiv class=\"product-sourcing\"\u003e\u003cp\u003eThis is a practitioner grade supplement. Depending on availability, it may include Mutaflor. If that brand is unavailable, your practitioner will recommend the most evidence-backed option for you.\u003c\/p\u003e\u003c\/div\u003e\u003cdiv class=\"product-short-description\"\u003e\u003cp\u003eMutaflor provides E. coli Nissle 1917, the most clinically documented E. coli probiotic strain, with over a century of evidence for ulcerative colitis maintenance, irritable bowel syndrome and gut microbiome restoration.\u003c\/p\u003e\u003c\/div\u003e\u003cdiv class=\"product-long-description\"\u003e\n\u003cp\u003eThis is a cold item. You must select express shipping so we may include cold pack protection for your sensitive products. Orders including cold items will only be shipped on Monday or Tuesday to preserve their temperature. Please refrigerate cold items as soon as you receive them.\u003c\/p\u003e\n\u003cp\u003eMutaflor 100 capsules\u003c\/p\u003e\n\u003cp\u003eMutaflor is registered in Australia for the relief and management of chronic constipation. Your healthcare practitioner may also utilise this strain for its pharmacological, metabolic and immunomodulation properties.\u003c\/p\u003e\n\u003cp\u003eStrain-Specific Characteristics of Escherichia coli strain Nissle 1917.\u003c\/p\u003e\n\u003cp\u003eThe ability to colonize\u003c\/p\u003e\n\u003cp\u003eAntagonistic activity, Inhibition of growth and or killing of pathogens\u003c\/p\u003e\n\u003cp\u003eAnti-invasive, prevention of colonisation in the gut by pathogens\u003c\/p\u003e\n\u003cp\u003eSynthesis of endogenous antimicrobial peptides-defensins\u003c\/p\u003e\n\u003cp\u003eMucosal integrity, contributing to luminal metabolism and stability of intestinal milieu-enhanced epithelial barrier function\u003c\/p\u003e\n\u003cp\u003eAnti-inflammatory and immunomodulatory effects\u003c\/p\u003e\n\u003cp\u003eStimulation of colonic mucosa\u003c\/p\u003e\n\u003cp\u003eServings per box: 100 capsules\u003c\/p\u003e\n\u003cp\u003eDirections for use\nAdults: The usual dosage of Mutaflor for Chronic Constipation in adults is: 3 to 4 capsules of Mutaflor per day.Please note that your health care professional may suggest alternative dosing specific to your situation.\u003c\/p\u003e\n\u003cp\u003eAllergen Information\nDoes not contain any milk proteins, gluten, wheat or lactose.\u003c\/p\u003e\n\u003cp\u003eMutaflor Ingredients:1 gastro-resistant hard capsule of Mutaflor contains 2.5 to 25 x 10^9 viable cells (CFU) of Escherichia coli Nissle 1917. The bacteria is lyophilized and filled into hard gelatine capsules which are enteric coated in order to open up when the terminal ileum is reached.Mutaflor should be stored refrigerated from 2 to 8 °C. A short interruption of refrigeration (3 or 4 days) does not do any harm to the product.\u003c\/p\u003e\n\u003cp\u003eProduct Education:\u003c\/p\u003e\n\u003cp\u003eThe origins of Mutaflor are somewhat less than auspicious. First isolated in 1917 from the faeces of a soldier in World War One who did not succumb to dysentery unlike most of his other comrades in regions that were highly contaminated by enteropathogens.\u003c\/p\u003e\n\u003cp\u003eMutaflor still today contains this very Nissle strain but manufactured in a modern GMP facility, lyophilized or freeze-dried, a process to remove moisture whilst the strain remains frozen and filled into gelatine capsules that are enteric coated in order that they do not open until the large intestine is reached.\u003c\/p\u003e\n\u003cp\u003eLong before even the advent of antibiotics the Physicians and Microbiologists at that time all understood the role of bacteria in disease but Professor Alfred Nissle had come to recognise that some faecal E.coli isolates showed signs of antagonistic action against pathogens in vitro.\u003c\/p\u003e\n\u003cp\u003eIt then becomes quite apparent as to why Nissle was only interested in the soldier who was not affected by dysentery.\u003c\/p\u003e\n\u003cp\u003eThe Human Microbiome is made up of all the bacterial colonies on and in the human body. This collection of bacteria numbers some 10 time\u003c\/p\u003e\n\u003c\/div\u003e\u003cdiv class=\"product-ingredients\"\u003e\n\u003ch3\u003eWhat's in it\u003c\/h3\u003e\n\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eIngredient\u003c\/th\u003e\n\u003cth\u003eForm\u003c\/th\u003e\n\u003cth\u003eDose\u003c\/th\u003e\n\u003cth\u003eNotes\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\u003ctr\u003e\n\u003ctd\u003eEscherichia coli Nissle 1917\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\u003cdiv class=\"product-how-to-take\"\u003e\n\u003ch3\u003eHow to take\u003c\/h3\u003e\n\u003cul\u003e\u003cli\u003eAs directed by your practitioner. Always refrigerate.\u003c\/li\u003e\u003c\/ul\u003e\n\u003c\/div\u003e\u003cdiv class=\"product-clinical-evidence\"\u003e\n\u003ch3\u003eClinical evidence\u003c\/h3\u003e\n\u003cul\u003e\u003cli\u003e\n\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/15479682\/\" target=\"_blank\"\u003eKruis et al. (2004), Maintaining remission of ulcerative colitis with the probiotic Escherichia coli Nissle 1917 is as effective as standard mesalazine (Gut)\u003c\/a\u003e \u003cspan class=\"evidence-note\"\u003e\u003cem\u003eEcN Nissle vs mesalazine UC maintenance RCT\u003c\/em\u003e\u003c\/span\u003e\n\u003c\/li\u003e\u003c\/ul\u003e\n\u003c\/div\u003e","brand":"Mutaflor","offers":[{"title":"Default Title","offer_id":67597395624210,"sku":"OL-BUNDLE-40273184981187-3","price":349.35,"currency_code":"AUD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0557\/2087\/0083\/files\/optilabs-review-mutaflor_cca04ae8-208f-4dbe-be46-f252e93a1b92.png?v=1792655205","url":"https:\/\/optilabs.com.au\/products\/mutaflor-3-pack-bundle","provider":"OptiLabs by Evergreen Doctors","version":"1.0","type":"link"}