{"title":"Brain \u0026 Mood","description":"\u003cp\u003eCognitive support, neurotransmitter precursors, neuroinflammation modulators, and mood-stabilising adaptogens.\u003c\/p\u003e","products":[{"product_id":"rn-labs-benfotiamine-1","title":"Benfotiamine (lipid-soluble B1)","description":"\u003ch2 class=\"product-marketing-headline\"\u003eFat soluble B1 that reaches nerve and brain tissue\u003c\/h2\u003e\u003cp class=\"product-tagline\"\u003e\u003cem\u003eFat-soluble B1 that goes where thiamine cannot.\u003c\/em\u003e\u003c\/p\u003e\u003cdiv class=\"product-sourcing\"\u003e\u003cp\u003eThis is a practitioner grade supplement. Depending on availability, it may include RN Labs. If that brand is unavailable, your practitioner will recommend the most evidence-backed option for you.\u003c\/p\u003e\u003c\/div\u003e\u003cdiv class=\"product-short-description\"\u003e\u003cp\u003eBenfotiamine is a lipid-soluble form of vitamin B1 (thiamine) with significantly higher bioavailability than standard thiamine. Used clinically to support glucose metabolism and nerve health in conditions of metabolic stress.\u003c\/p\u003e\u003c\/div\u003e\u003cdiv class=\"product-long-description\"\u003e\n\u003cp\u003eRN Labs Benfotiamine 25g Powder\u003c\/p\u003e\n\u003cp\u003eSummary\u003c\/p\u003e\n\u003cp\u003ePure compound known as benfotiamine, a lipid-soluble form of vitamin B1 (Thiamine)\u003c\/p\u003e\n\u003cp\u003eBenfotiamine has been used clinically to improve glucose metabolism\u003c\/p\u003e\n\u003cp\u003eDensity: 1 ml (1 Scoop) equivalent to 670 mg (0.670 g\/mL)\u003c\/p\u003e\n\u003cp\u003eFree from gluten, dairy, egg, yeast, soy and sugar\u003c\/p\u003e\n\u003cp\u003eVegan friendly\u003c\/p\u003e\n\u003cp\u003eDosage\u003c\/p\u003e\n\u003cp\u003eFor extemporaneous use only\u003c\/p\u003e\n\u003cp\u003eCommon dosage range: 100, 600 mg daily; can be taken with or without food\u003c\/p\u003e\n\u003cp\u003eIt is advisable to begin supplementation at the low end of the dose range, increasing if required\u003c\/p\u003e\n\u003cp\u003eWarnings\u003c\/p\u003e\n\u003cp\u003eIf pregnant, consult your healthcare practitioner before using this product\u003c\/p\u003e\n\u003cp\u003ePractitioners should conduct ongoing research and take care to follow their practitioner association guidelines for appropriate administration of compounding ingredients\u003c\/p\u003e\n\u003cp\u003eDietary supplements should not replace a balanced diet\u003c\/p\u003e\n\u003c\/div\u003e\u003cdiv class=\"product-ingredients\"\u003e\n\u003ch3\u003eWhat's in it\u003c\/h3\u003e\n\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eIngredient\u003c\/th\u003e\n\u003cth\u003eForm\u003c\/th\u003e\n\u003cth\u003eDose\u003c\/th\u003e\n\u003cth\u003eNotes\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\u003ctr\u003e\n\u003ctd\u003eBenfotiamine (S-benzoylthiamine O-monophosphate)\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003ctd\u003e\u003c\/td\u003e\n\u003c\/tr\u003e\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\u003cdiv class=\"product-clinical-evidence\"\u003e\n\u003ch3\u003eClinical evidence\u003c\/h3\u003e\n\u003cul\u003e\u003cli\u003e\n\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/18184923\/\" target=\"_blank\"\u003eBenfotiamine and diabetic neuropathy, randomised controlled trial\u003c\/a\u003e \u003cspan class=\"evidence-note\"\u003e\u003cem\u003eBenfotiamine improves nerve conduction and reduces neuropathy scores versus placebo\u003c\/em\u003e\u003c\/span\u003e\n\u003c\/li\u003e\u003c\/ul\u003e\n\u003c\/div\u003e","brand":"Practitioner grade","offers":[{"title":"Default Title","offer_id":51124004847890,"sku":null,"price":31.95,"currency_code":"AUD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0557\/2087\/0083\/files\/optilabs-supp-rn-labs-benfotiamine-1.jpg?v=1786431502"},{"product_id":"nutripath-advanced-neurotransmitter-profile","title":"Advanced neurotransmitter profile","description":"\u003ch2 class=\"product-marketing-headline\"\u003eA full neurotransmitter picture for complex cases\u003c\/h2\u003e\u003cp class=\"product-scientific-tagline\"\u003eComprehensive neurotransmitter and metabolite profile.\u003c\/p\u003e\u003cp class=\"product-short-description\"\u003eA full neurotransmitter profile measuring the major excitatory and inhibitory messengers and their metabolites, for complex mood and focus presentations.\u003c\/p\u003e\u003cdiv class=\"product-long-description\"\u003eThis profile measures the major neurotransmitters and their metabolites together, rather than in isolation, which matters because they operate as a balanced system. It is intended for complex mood, focus and anxiety presentations where a simpler investigation has not clarified the picture. A practitioner consultation is included, as interpretation requires clinical context.\u003c\/div\u003e","brand":"NutriPath","offers":[{"title":"Default Title","offer_id":52591865430290,"sku":"OPTI-NUTRIPATH-ADVANCED-NEUROTRANSMITTER-PROFILE","price":469.0,"currency_code":"AUD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0557\/2087\/0083\/files\/optilabs-supp-nutripath-neurotransmitter-testing-advanced.png?v=1786431089"},{"product_id":"nutripath-organic-acids-metabolomic-profile","title":"Organic acids metabolomic profile (at-home urine)","description":"\u003ch2 class=\"product-marketing-headline\"\u003eSee the metabolic picture behind mood and focus\u003c\/h2\u003e\u003cp class=\"product-brand-attribution\"\u003eTest processed by \u003cstrong\u003eNutriPath\u003c\/strong\u003e (Test Code 4041)\u003c\/p\u003e\u003cdiv class=\"product-short-description\"\u003e\u003cp\u003eA urinary organic acids profile that maps cellular energy production, neurotransmitter turnover, detoxification and gut microbial markers from a single at-home urine sample.\u003c\/p\u003e\u003c\/div\u003e\u003cdiv class=\"product-long-description\"\u003e\u003cp\u003eOrganic acids are metabolic by-products that reveal how well the body produces energy, processes neurotransmitters and clears waste. Marked accumulation of specific organic acids in urine often signals a metabolic block, which may reflect a nutrient shortfall, an enzyme issue, toxic build-up or a medication effect. This profile measures markers across mitochondrial energy production, B-vitamin and antioxidant status, and neurotransmitter breakdown, which makes it useful for investigating low mood, poor focus, fatigue and brain fog. Collected at home from a single urine sample.\u003c\/p\u003e\u003c\/div\u003e\u003cdiv class=\"product-tga-note\"\u003e\u003csmall\u003e\u003cstrong\u003eRegulatory note: \u003c\/strong\u003eThis is a health information tool. Results should be reviewed with a qualified practitioner.\u003c\/small\u003e\u003c\/div\u003e","brand":"NutriPath","offers":[{"title":"Default Title","offer_id":52591869427986,"sku":"OPTI-NUTRIPATH-ORGANIC-ACIDS-METABOLOMIC-PROF","price":422.0,"currency_code":"AUD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0557\/2087\/0083\/files\/nutripath-organic-acids-metabolomic-profile.jpg?v=1786431108"},{"product_id":"brain-and-mood-plan","title":"Brain \u0026 Mood Bundle","description":"\u003cp\u003e\u003c\/p\u003e","brand":"OptiLabs","offers":[{"title":"Consult only","offer_id":52591871983890,"sku":"plan-bm-consult","price":49.0,"currency_code":"AUD","in_stock":true},{"title":"Consult + Starter Bundle","offer_id":52591872016658,"sku":"plan-bm-starter","price":610.0,"currency_code":"AUD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0557\/2087\/0083\/files\/optilabs-hub-brain-and-mood_4a57f8d1-9b7c-4c22-a64a-33c6a9e89c06.jpg?v=1786431126"},{"product_id":"nutripath-active-b12-and-folate-blood-test","title":"Active B12 and folate blood test","description":"\u003ch2 class=\"product-marketing-headline\"\u003eThe B12 test that catches what standard testing misses\u003c\/h2\u003e\u003cp class=\"product-tagline\"\u003e\u003cem\u003eActive B12 (holotranscobalamin) and active folate (5-MTHF). A more accurate picture of functional B vitamin status than standard total B12 testing.\u003c\/em\u003e\u003c\/p\u003e\u003cp class=\"product-brand-attribution\"\u003eTest processed by \u003cstrong\u003eNutriPath\u003c\/strong\u003e\u003c\/p\u003e\u003cdiv class=\"product-short-description\"\u003e\u003cp\u003eMeasures active B12 (holotranscobalamin, the fraction your cells can actually use) and active folate (5-methyltetrahydrofolate, the form your cells use directly). More sensitive than standard serum B12 and total folate testing, particularly for anyone with methylation variations or neurological symptoms.\u003c\/p\u003e\u003c\/div\u003e\u003cdiv class=\"product-long-description\"\u003e\u003cp\u003eStandard serum B12 testing has a known sensitivity problem. The total serum B12 number includes both the active fraction (bound to transcobalamin II, which is the part your cells actually take up) and the inactive fraction (bound to haptocorrin, which is metabolically useless). People can have normal total B12 but low active B12, with consequent fatigue, cognitive symptoms, nerve tingling or anaemia. Active B12 testing, also called holotranscobalamin or HoloTC, measures only the functional fraction and catches deficiency that standard testing misses. Active folate measurement (5-MTHF) adds similar value, particularly in people with MTHFR variants who cannot efficiently convert folic acid into the usable 5-MTHF form. Together these markers are the more accurate modern approach to B vitamin status assessment.\u003c\/p\u003e\u003c\/div\u003e\u003cdiv class=\"product-ingredients\"\u003e\n\u003ch3\u003eWhat it measures\u003c\/h3\u003e\n\u003ctable\u003e\n\u003cthead\u003e\u003ctr\u003e\n\u003cth\u003eBiomarker\u003c\/th\u003e\n\u003cth\u003eSample\u003c\/th\u003e\n\u003cth\u003eReference Range\u003c\/th\u003e\n\u003cth\u003eWhat it tells you\u003c\/th\u003e\n\u003c\/tr\u003e\u003c\/thead\u003e\n\u003ctbody\u003e\n\u003ctr\u003e\n\u003ctd\u003eActive B12 (Holotranscobalamin)\u003c\/td\u003e\n\u003ctd\u003eBlood (SST)\u003c\/td\u003e\n\u003ctd\u003eAbove 50 pmol\/L optimal\u003c\/td\u003e\n\u003ctd\u003eThe metabolically active fraction of B12 that your cells can actually take up. Low active B12 with normal total B12 is a commonly missed pattern.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003ctr\u003e\n\u003ctd\u003eActive Folate (5-MTHF)\u003c\/td\u003e\n\u003ctd\u003eBlood (EDTA)\u003c\/td\u003e\n\u003ctd\u003eAbove 10 nmol\/L optimal\u003c\/td\u003e\n\u003ctd\u003eThe biologically active form of folate that your cells use directly. More informative than total folate in anyone with MTHFR variants or methylation concerns.\u003c\/td\u003e\n\u003c\/tr\u003e\n\u003c\/tbody\u003e\n\u003c\/table\u003e\n\u003c\/div\u003e\u003cdiv class=\"product-how-to-take\"\u003e\n\u003ch3\u003eHow to collect and what to expect\u003c\/h3\u003e\n\u003cp\u003eNo fasting required. Book at any NutriPath referral centre. If taking B12 supplements or B complex, hold doses for 24 hours before collection for the clearest baseline. Results in 3 to 5 business days.\u003c\/p\u003e\n\u003c\/div\u003e\u003cdiv class=\"product-warnings\"\u003e\n\u003ch3\u003eWarnings and cautions\u003c\/h3\u003e\n\u003cp\u003eThis is a health information test. Do not self treat neurological symptoms based on results. Suspected B12 deficiency with neurological involvement requires GP assessment and usually prompt treatment to prevent permanent nerve damage.\u003c\/p\u003e\n\u003c\/div\u003e\u003cdiv class=\"product-faqs\"\u003e\n\u003ch3\u003eCommon questions\u003c\/h3\u003e\n\u003cdetails\u003e\u003csummary\u003e\u003cstrong\u003eI was tested for B12 and it came back normal. Why might this test be different?\u003c\/strong\u003e\u003c\/summary\u003e\u003cp\u003eStandard B12 tests measure total B12, which includes an inactive fraction that your cells cannot use. Active B12 (holotranscobalamin) measures only the functional fraction. It is possible to have normal total B12 and low active B12, which this test catches.\u003c\/p\u003e\u003c\/details\u003e\u003cdetails\u003e\u003csummary\u003e\u003cstrong\u003eWho should consider this over standard B12 testing?\u003c\/strong\u003e\u003c\/summary\u003e\u003cp\u003eAnyone with fatigue, cognitive symptoms, tingling or nerve symptoms with a borderline or low normal standard B12. Vegans and vegetarians. Anyone over 65 (absorption declines with age). Anyone on metformin or long term proton pump inhibitors (both deplete B12). Anyone with known methylation variants.\u003c\/p\u003e\u003c\/details\u003e\u003cdetails\u003e\u003csummary\u003e\u003cstrong\u003eWhat about folic acid on food labels?\u003c\/strong\u003e\u003c\/summary\u003e\u003cp\u003eFolic acid is the synthetic form added to flour, breakfast cereals and many supplements. Your body must convert it to 5-MTHF to use it, a process that is inefficient in people with MTHFR variants. Active folate testing shows you what you actually have available, not just what you have eaten.\u003c\/p\u003e\u003c\/details\u003e\u003cdetails\u003e\u003csummary\u003e\u003cstrong\u003eIf I am deficient, what form of B12 supplement should I use?\u003c\/strong\u003e\u003c\/summary\u003e\u003cp\u003eFor most people, methylcobalamin or hydroxocobalamin are preferred over cyanocobalamin. Sublingual forms bypass absorption issues. In documented pernicious anaemia, intramuscular injections remain the standard of care.\u003c\/p\u003e\u003c\/details\u003e\n\u003c\/div\u003e\u003cdiv class=\"product-clinical-evidence\"\u003e\n\u003ch3\u003eClinical evidence\u003c\/h3\u003e\n\u003cul\u003e\n\u003cli\u003e\n\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/19318471\/\" target=\"_blank\" rel=\"noopener\"\u003eActive B12 (holotranscobalamin) in clinical practice\u003c\/a\u003e: Evidence that active B12 outperforms total B12 in detecting functional deficiency.\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23633203\/\" target=\"_blank\" rel=\"noopener\"\u003e5-MTHF and MTHFR polymorphism\u003c\/a\u003e: Review of folate metabolism and clinical implications of MTHFR variants.\u003c\/li\u003e\n\u003cli\u003e\n\u003ca href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/23595586\/\" target=\"_blank\" rel=\"noopener\"\u003eB12 deficiency and neurological symptoms\u003c\/a\u003e: Why prompt identification matters for neurological outcomes.\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e","brand":"NutriPath","offers":[{"title":"Default Title","offer_id":52591876735250,"sku":"OPTI-NUTRIPATH-ACTIVE-B12-AND-FOLATE-BLOOD-TE","price":169.0,"currency_code":"AUD","in_stock":true}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/0557\/2087\/0083\/files\/nutripath-active-b12-and-folate-blood-test.jpg?v=1786431156"}],"url":"https:\/\/optilabs.com.au\/collections\/brain-and-mood.oembed","provider":"OptiLabs by Evergreen Doctors","version":"1.0","type":"link"}